Adriana Maria Louro Gonçalves

PhD Fellow

aml.goncalves@campus.fct.unl.pt

Short Biography

Adriana received her Master degree in Materials Engineering from Faculdade de Ciências e Tecnologia, Universidade Nova de
Lisboa, in 2019. Her master dissertation titled: "Production and characterization of thermoresponsive magnetic membranes"
focused on the development of dual-stimuli composite membranes composed of hybrid thermoresponsive microgels for magnetic
hyperthermia applications. The work developed during her thesis resulted in a published article titled: "Incorporation of
Dual-Stimuli Responsive Microgels in Nanofibrous Membranes for Cancer Treatment by Magnetic Hyperthermia". Currently she
has enrolled as a research fellow in the Soft and Biofunctional Materials Group at CENIMAT|i3N inserted in the project DREaMM
- Engineering of Dual-stimuli Responsive nanofibrous Magnetic Membranes (PTDC/CTM-CTM/30623/2017), under the supervision of
Dr. Paula Soares. Her current research focuses on the development of electrospun polymeric membranes, incorporated with thermosensitive
PNIPAAm microgels and iron oxide magnetic nanoparticles for controlled drug delivery and magnetic hyperthermia. In 2020 her
work was selected for an oral presentation at nanoPT2020 titled: "Production and characterization of thermoresponsive magnetic
membranes". Her main research interests are thermoresponsive microgels, magnetic hyperthermia, colloidal electrospinning and
drug delivery.

Education

2014/09 – 2019/10/16 Frequentou Engenharia de Materiais (Mestrado integrado) Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal “Produção e Caracterização de Membranas Magnéticas Termoresponsivas” (TESE/DISSERTAÇÃO) 16

Publications

Adriana Gonçalves; Joana Matos; Raquel Cabrita; Inês Rodrigues; João Paulo Borges; Paula I. P. Soares. “Development of Magnetic Nanofibrous Membranes for Localized Solid Cancer Treatment”. 2022. 10.3390/materproc2022008119

Adriana Gonçalves; João Paulo Borges; Miguel Castilho; Paula I. P. Soares. “Magneto- and Thermoresponsive Systems: A Review of Their Application in Cancer Theranostics”. Advanced Healthcare Materials (2026): https://doi.org/10.1002/adhm.202502825. 10.1002/adhm.202502825

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https://doi.org/10.1002/adhm.202502825

Adriana Gonçalves; Susete N. Fernandes; A. Sofia Pádua; Jorge Carvalho Silva; João Paulo Borges; Miguel Castilho; Paula I.P. Soares. “Developing thermoresponsive p(NIPAAm-HMAAm) electrospun nanofibers for on-demand drug release of doxorubicin”. Journal of Drug Delivery Science and Technology (2025): https://doi.org/10.1016/j.jddst.2025.107244. 10.1016/j.jddst.2025.107244

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https://doi.org/10.1016/j.jddst.2025.107244

Adriana Gonçalves; Raquel Cabrita; Joana Matos; Inês Rodrigues; Tânia Vieira; João Paulo Borges; Paula I.P. Soares. “Dual-stimuli-responsive poly(vinyl alcohol) nanofibers for localized cancer treatment: Magnetic hyperthermia and drug release studies”. Journal of Drug Delivery Science and Technology (2024): https://doi.org/10.1016/j.jddst.2024.105492. 10.1016/j.jddst.2024.105492

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https://doi.org/10.1016/j.jddst.2024.105492

Gonçalves, Adriana; Simões, Beatriz T.; Almeida, Filipe V.; Susete N. Fernandes; Manuel Valente; Tânia Vieira; Henriques, Célia; Borges, João P. M. R. (1A16-9D5A-3956); Paula I. P. Soares. “Engineering dual-stimuli responsive poly(vinyl alcohol) nanofibrous membranes for cancer treatment by magnetic hyperthermia”. Biomaterials Advances 145 (2022): 10.1016/j.bioadv.2022.213275.

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10.1016/j.bioadv.2022.213275

David Jíménez-Arias; Sarai Morales-Sierra; Patrícia Silva; Henrique Carrêlo; Gonçalves, Adriana; José Filipe Teixeira Ganança; Nuno Nunes; et al. “Encapsulation with Natural Polymers to Improve the Properties of Biostimulants in Agriculture”. Plants (2022): https://doi.org/10.3390/plants12010055. 10.3390/plants12010055

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https://doi.org/10.3390/plants12010055

Adriana Gonçalves; Filipe V. Almeida; João Paulo Borges; Paula I. P. Soares. “Incorporation of Dual-Stimuli Responsive Microgels in Nanofibrous Membranes for Cancer Treatment by Magnetic Hyperthermia”. Gels 7 28 (2021): https://doi.org/10.3390/gels7010028. Acesso aberto • Publicado • 10.3390/gels7010028

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https://doi.org/10.3390/gels7010028

Paula I. P. Soares; Gonçalves, Adriana; Limón, David; A. Sofia Pádua; Leal, Catarina R.; Lança, M Carmo; Ana C. Baptista; et al. “Soft and Biofunctional Materials Group: Biomaterias for medical applications and Tissue enginnering”. Trabalho apresentado em NOVA FCT Science Days, 2025.

Gonçalves, Adriana; Castilho, Miguel; Paula I. P. Soares; Borges, João P. M. R. (1A16-9D5A-3956). “Development of thermoresponsive scaffolds for controlled and localized drug release”. Trabalho apresentado em 33rd Annual Conference of the European Society for Biomaterials (ESB 2023), 2023.

Gonçalves, Adriana; Castilho, Miguel; Borges, João P. M. R. (1A16-9D5A-3956); Soares, Paula I. P.. “Electrospun PNIPAAm-based fibers for pH- and thermo-responsive localized drug release”. Trabalho apresentado em 32nd Annual Conference of the European Society for Biomaterials (ESB2022), 2022.

Gonçalves, Adriana; Oliveira, Leonor; Castilho, Miguel; Borges, João P. M. R. (1A16-9D5A-3956); Soares, Paula I. P.. “Electrospinning of thermoresponsive based polymers for controlled and localized drug release”. Trabalho apresentado em RSC CNN Early Career Researcher Virtual Poster Meeting 2022, 2022.

Gonçalves, Adriana; Matos, Joana; Cabrita, Raquel; Rodrigues, Inês; Silva, Jorge Carvalho; Borges, João P. M. R.; Soares, Paula I. P.. “Development of magnetic nanofibrous membranes for localized solid cancer treatment”. Trabalho apresentado em Materiais 2022, 2022.

Almeida, Filipe; Simões, Beatriz T.; Gonçalves, Adriana; Borges, João; Soares, Paula I. P.. Autor correspondente: Almeida, Filipe. “Extracellular hyperthermia for adjuvant treatment of advance cutaneous melanoma using superparamagnetic iron oxide nanoparticles and dual-stimuli responsive composites”. Trabalho apresentado em 31st Conference of the European Society for Biomaterials, 2021.

Gonçalves, Adriana; Almeida, Filipe V.; Soares, Paula I. P.; Borges, João. “Production and characterization of dual-stimuli nanofibrous membranes”. Trabalho apresentado em 31st Conference of the European Society for Biomaterials, 2021.

Filipe Almeida; Beatriz Simões; Adriana Gonçalves; João Paulo Borges; Paula Soares. “Extracellular Hyperthermia for Adjuvant Treatment of Advanced Cutaneous Melanoma using Superparamagnetic Iron Oxide Nanoparticles and Dual-Stimuli Composites”. Trabalho apresentado em 31st Annual Conference of the European Society for Biomaterials, 2021.

Paula Soares; Adriana Gonçalves; João Lavadinho; Ricardo Matos; João Magalhães; João Paulo Borges. “Development of a new magnetically responsive device for localized cancer theranostics”. Trabalho apresentado em 31st Conference of the European Society for Biomaterials, 2021.

Soares, Paula I. P.; Gonçalves, Adriana; Matos, Ricardo J.R.; Lavadinho, João; Romão, Joana; Borges, João. “Dual-stimuli responsive device based on thermoresponsive polymers and magnetic nanoparticles for cancer theranostic”. Trabalho apresentado em 11th World Biomaterials Congress, 2020.

Projects

Designação Financiadores

2022/01/01 – 2025/12/16 Development of a new magnetically responsive implantable 3D device for localized cancer theranostics 2021.06558.BD Bolseiro de Doutoramento Universidade Nova de Lisboa Centro de Investigação em Materiais, PortugalUniversidade Nova de Lisboa Departamento de Ciência dos Materiais, Portugal Fundação para a Ciência e a Tecnologia Em curso